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  • Disease Overview
    • About hATTR
    • Disease Manifestations
    • How to Diagnose
  • How It Works
    • Mechanism of Action
    • TTR Suppression
  • Trial Design & Efficacy
    • Study Design
    • Efficacy
    • Additional Data
  • Safety
  • Dosing & Administration
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    • Access & Support
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Disease Manifestations
Efficacy
Safety
Access & Support

WAINUA is indicated for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis (hATTR-PN) in adults.

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DISEASE OVERVIEW

  • About hATTR
  • Disease Manifestations
  • How to Diagnose

How It Works

  • Mechanism of Action
  • TTR Suppression

TRIAL DESIGN & EFFICACY

  • Study Design
  • Efficacy
  • Additional Data
  • Safety

Dosing & Administration

Access & RESOURCES

  • Access & Support
  • Resources
  • FAQs

Stay Informed

Request a Rep

IMPORTANT SAFETY INFORMATION

WARNINGS AND PRECAUTIONS

  • Reduced Serum Vitamin A Levels and Recommended Supplementation WAINUA leads to a decrease in serum vitamin A levels. Supplement with recommended daily allowance of vitamin A. Refer patient to an ophthalmologist if ocular symptoms suggestive of vitamin A deficiency occur.

ADVERSE REACTIONS

Most common adverse reactions (≥9% in WAINUA-treated patients) were vitamin A decreased (15%) and vomiting (9%).

INDICATION

WAINUA injection, for subcutaneous use, 45 mg is indicated for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults.

Please see the full Prescribing Information.

You may report side effects related to AstraZeneca products.

IMPORTANT SAFETY INFORMATION

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This product information is intended for US Healthcare Professionals only.

WAINUA is a registered trademark, and AstraZeneca Access 360 is a trademark of the AstraZeneca group of companies.

©2026 AstraZeneca. All rights reserved. US-104306 Last Updated 3/26US-107583 Last Updated 4/26

©2026 AstraZeneca. All rights reserved.
US-104306 Last Updated 3/26 US-107583 Last Updated 4/26